KPUCOMBO *A 5-in-1 solution for the KPU horse, combining EquiNatural's SiboCARE, GutAminos, P5P, B12-Balance, and Spirulina, into one comprehensive blend
📦 Combo Savings! Pay 5% less than individual prices
Tackle the complexities of Cryptopyrroluria (KPU) with KPUCOMBO, a powerful 5-in-1 blend combining EquiNatural's SiboCARE , GutAminos , P5P , B12-Balance & organic Spirulina.
This synergistic formula stabilises the hindgut, reconnects the gut:liver pathway, and supports detoxification for long-term health and wellbeing.
✨ “My horse is transformed - faecal water gone, energy up, and coat shining!” Megan
✨ “From spooky to sparkly - trotting up hills and loving life again!” Natalie & Dewi
💡Top Tip
If your horse needs significantly more support, i.e. gut pain/inflammation and a detoxification system reset, see our full 2-month / 3-stage See our KPU RESET PROGRAMME for the complete KPU detoxification protocol, including proactive support suggestions thereafter.
Overview
What is KPU?
Cryptopyrroluria (KPU) is a widespread, multi-metabolic detoxification disorder often referred to as "the disease with a thousand faces" due to its extensive range of symptoms. These can include persistent gut issues, skin and hoof problems, musculoskeletal challenges, unexplained swelling, and more.
At its root, KPU stems from a disrupted hindgut microbiome, leading to a deficiency in Pyridoxal-5-Phosphate (P5P), the activated form of vitamin B6. This deficiency impairs the liver's detoxification process, allowing toxins to accumulate and disrupt overall health.
How KPUCOMBO helps
KPUCOMBO provides targeted support to rebalance the hindgut microbiome, restore the gut-liver pathway, and enhance the body's natural detoxification processes.
Important Note
KPUCOMBO is a nutritional, functional food supplement and not veterinary medicine. For more information, refer to Dr Kellon's Horse Sense - Nutrition is not 'Alternative' Therapy .
For the latest KPU updates, see our main A-Z Equine Condition/KPU page in the Advice Centre above.
Composition & Feed Guide
* Each item is available separately in our KPU Shop page.
Combined Herbal Blend
Human-grade, produced to ecological standards and free from agro-chemicals. See our Quality page for Organic Certification Documents.
A combination of EquiNatural's SiboCARE
, GutAminos
, P5P
(Activated B6), B12-Balance
& Spirulina
, combined together as one convenient feed supplement.
- 13g/100kg bodyweight per day, i.e. 66g for a 500kg horse.
- For fussy eaters, start with a pinch and slowly build your way up.
- 1-yr shelf life.
*
Supplements of any kind should be fed with caution to the pregnant or nursing mare so always seek veterinary advice.
Recommended
- If your horse is showing signs of discomfort or stress, alleviate with our our DuoBute / StressTonic.
- Following the KPUCOMBO, feed our LKLCARE to detox and tone the major detoxification organs - the liver, kidneys, and lymph nodes. Alternatively, see our KPU Reset Programme.
- Finally, quality meadow hay , fed 24/7, is going to be your saviour here to help restore the beneficial hindgut microbiome.
Client Feedback
Clients have reported transformative results with KPUCOMBO, highlighting improvements in faecal water, energy levels, coat condition, mobility, and overall wellbeing. Horses have shown rapid changes in behaviour, posture, and appetite, with some owners seeing results in just a few days. Highlights includes:
- Dramatic reductions in faecal water and improvements in gut health.
- Significant behavioural changes, including calmer demeanours and increased energy.
- Improvements in coat, hoof quality, and overall physical condition.
- Positive impacts on musculoskeletal health and mobility.